Therapeutic Targets of Monoclonal Antibodies Used in the Treatment of Cancer: Current and Emerging.

ABSTRACT: Cancer is one of the leading global causes of death and disease, and treatment options are constantly evolving. In this sense, the use of monoclonal antibodies (mAbs) in immunotherapy has been considered a fundamental aspect of modern cancer therapy. In order to avoid collateral damage, it is indispensable to identify specific molecular targets or biomarkers of therapy and/or diagnosis (theragnostic) when designing an appropriate immunotherapeutic regimen for any type of cancer. Furthermore, it is important to understand the currently employed mAbs in immunotherapy and their mechanisms of action in combating cancer. To achieve this, a comprehensive understanding of the biology of cancer cell antigens, domains, and functions is necessary, including both those presently utilized and those em

SUBMITTER: Effer B 

PROVIDER: S-EPMC10377242 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature