Individual and joint associations of anxiety disorder and depression with cardiovascular disease: A UK Biobank prospective cohort study.

ABSTRACT:

Background

Growing evidence suggests that individuals with anxiety disorder have an elevated risk of cardiovascular disease (CVD) but few studies have assessed this association independently of or jointly with depression.

Methods

We conducted a prospective cohort study using UK Biobank. Diagnoses of anxiety disorder, depression, and CVDs were ascertained through linked hospital admission and mortality data. Individual and joint associations between anxiety disorder and depression and CVD overall, as well as each of myocardial infarction, stroke/transient ischemic attack, and heart failure, were analyzed using Cox proportional hazard models and interaction tests.

Results

Among the 431,973 participants, the risk of CVD was higher among those who had been diagnosed with

SUBMITTER: Nakada S 

PROVIDER: S-EPMC10377450 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature