Preoperative CT-Based Skeletal Muscle Mass Depletion and Outcomes after Total Laryngectomy.

ABSTRACT:

Purpose

To assess the role of preoperative CT-based skeletal muscle mass depletion on postoperative clinical outcomes and survival in patients who underwent total laryngectomy for cancer.

Methods

Patients operated on between January 2011 and March 2020 were retrospectively included. Skeletal muscle area and intra- and inter-muscular fat accumulation were measured at the third lumbar vertebral level on preoperative CT scans. Skeletal muscle mass depletion was defined based on pre-established cut-off values. Their association with postoperative morbidity, length of stay (LOS), costs, and survival was assessed.

Results

A total of 84 patients were included, of which 37 (44%) had preoperative skeletal muscle mass depletion. The rate of postoperative fistula (23% vs. 35%, <

SUBMITTER: Salati V 

PROVIDER: S-EPMC10377557 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature