Developing Oncolytic Viruses for the Treatment of Cervical Cancer.

ABSTRACT: Cervical cancer represents one of the most important malignancies among women worldwide. Current therapeutic approaches for cervical cancer are reported not only to be inadequate for metastatic cervical cancer, but are also considered as cytotoxic for several patients leading to serious side effects, which can have negative implications on the quality of life of women. Therefore, there is an urgent need for the development of innovative and effective treatment options. Oncolytic viruses can eventually become effective biological agents, since they preferentially infect and kill cancer cells, while leaving the normal tissue unaffected. Moreover, they are also able to leverage the host immune system response to limit tumor growth. This review aims to systematically describe and discuss the d

SUBMITTER: Kalafati E 

PROVIDER: S-EPMC10377776 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature