Immunonutrition in Radical Cystectomy: State of the Art and Perspectives.

ABSTRACT: Preoperative nutritional status is a pivotal aspect to consider in patients with cancer undergoing radical cystectomy (RC), as those at risk of malnutrition or already malnourished are more prone to post-surgical complications. The loss of muscle mass is a major consequence of cancer-related malnutrition. It is associated with increased risk of hospital readmission, longer hospitalization, and higher mortality. Nowadays, the close relationship between nutritional and immunological aspects under stressful conditions, such as surgery, represents an emerging scientific and clinical issue. Indeed, the synergistic action of reduced food intake and systemic inflammation generates metabolic derangements with tissue catabolism, including skeletal muscle breakdown, which is, in turn, associated wit

SUBMITTER: Casirati A 

PROVIDER: S-EPMC10378592 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature