The extent of anticholinergic burden across an older Welsh population living with frailty: cross-sectional analysis of general practice records.

ABSTRACT:

Background

Anticholinergic medicines are associated with adverse outcomes for older people. However, little is known about their use in frailty. The objectives were to (i) investigate the prevalence of anticholinergic prescribing for older patients, and (ii) examine anticholinergic burden according to frailty status.

Methods

Cross-sectional analysis of Welsh primary care data from the Secure Anonymised Information Linkage databank including patients aged ≥65 at their first GP consultation between 1 January and 31 December 2018. Frailty was identified using the electronic Frailty Index and anticholinergic burden using the Anticholinergic Cognitive Burden (ACB) scale. Descriptive analysis and logistic regression were conducted to (i) describe the type and frequency of antichol

SUBMITTER: Cheong VL 

PROVIDER: S-EPMC10378723 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature