The Next Frontier in ART: Harnessing the Uterine Immune Profile for Improved Performance.

ABSTRACT: Assisted reproduction techniques have improved considerably in recent decades, but despite these advances, success rates remain relatively low. Endometrial immune profiling involves the analysis of cytokine biomarkers in the endometrium during the mid-luteal phase. This profiling aims to provide insights into the immune environment of the uterus. The aim is to identify immune disturbances and thus guide the development of personalized therapeutic approaches. The first part of the review looks back at the emergence of innovative concepts, highlighting the specificity of the human uterine environment at the time of implantation. Based on this new knowledge, biomarkers have been selected for endometrial immune profiling. The second part details the results of clinical studies conducted over t

SUBMITTER: Ledee N 

PROVIDER: S-EPMC10379072 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature