Synergistic Effects of Vitis vinifera L. and Centella asiatica against CCl₄-Induced Liver Injury in Mice.

ABSTRACT: Liver injury can be acute or chronic, resulting from a variety of factors, including viral hepatitis, drug overdose, idiosyncratic drug reaction, or toxins, while the progression of pathogenesis in the liver rises due to the involvement of numerous cytokines and growth factor mediators. Thus, the identification of more effective biomarker-based active phytochemicals isolated from medicinal plants is a promising strategy to protect against CCl₄-induced liver injury. Vitis vinifera L. (VE) and Centella asiatica (CE) are well-known medicinal plants that possess anti-inflammatory and antioxidant properties. However, synergism between the two has not previously been studied. Here, we investigated the synergistic effects of a V. vinifera L. (VE) leaf, C. asiati

SUBMITTER: Munakarmi S 

PROVIDER: S-EPMC10379123 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature