Effects of Vasopressin Receptor Agonists during the Resuscitation of Hemorrhagic Shock: A Systematic Review and Meta-Analysis of Experimental and Clinical Studies.

ABSTRACT:

Background

The clinical impact of vasopressin in hemorrhagic shock remains largely unknown.

Objective

This systematic review and meta-analysis was designed to investigate the effects of vasopressin receptor agonists during the resuscitation of hemorrhagic shock.

Methods

A systematic search of PubMed (MEDLINE), Scopus, and PubMed Central was conducted for relevant articles. Experimental (animal) and clinical studies were included. The primary objective was to investigate the correlation of vasopressin receptor agonist use with mortality and various hemodynamic parameters.

Results

Data extraction was possible in thirteen animal studies and two clinical studies. Differences in risk of mortality between patients who received a vasopressin receptor agonist were not

SUBMITTER: Laou E 

PROVIDER: S-EPMC10381354 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature