The Gastrointestinal Tract Is Pinpointed as a Reservoir of Candida albicans, Candida parapsilosis, and Candida tropicalis Genotypes Found in Blood and Intra-Abdominal Samples.

ABSTRACT:

Background

Candida spp., as part of the microbiota, can colonise the gastrointestinal tract. We hypothesised that genotyping Candida spp. isolates from the gastrointestinal tract could help spot genotypes able to cause invasive infections.

Materials/methods

A total of 816 isolates of C. albicans (n = 595), C. parapsilosis (n = 118), and C. tropicalis (n = 103) from rectal swabs (n = 754 patients) were studied. Genotyping was conducted using species-specific microsatellite markers. Rectal swab genotypes were compared with previously studied blood (n = 814) and intra-abdominal (n = 202) genotypes.

Results

A total of 36/754 patients had the same Candida spp. isolated from blood cultures, intra-abdominal samples, or both; these pa

SUBMITTER: Mesquida A 

PROVIDER: S-EPMC10381600 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature