The protective effect of inactivated Flavobacterium columnare vaccine in grass carp (Ctenopharyngodon idellus).

ABSTRACT: Flavobacterium columnare, which causes columnaris disease, is responsible for significant mortality in grass carp. Vaccination is a safe and effective measure to combat this disease, and this study aimed to investigate the immune protective effects of different treatments using an inactivated F. columnare vaccine. The vaccine was prepared by inactivating the bacteria with 0.05% formaldehyde at 4°C for 24 hours. The experiments involving grass carp were divided into two parts. In Experiment 1, the immune effects of two isolates, JX-01 (genomovar I) and MU-04 (genomovar II), were compared, along with the impact of white oil adjuvant and the number of immunizations. The results showed that when the white oil adjuvant was used as a booster, the relative percent survival (RPS) of

SUBMITTER: Guo W 

PROVIDER: S-EPMC10381957 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature