NT-proBNP and All-Cause and Cardiovascular Mortality in US Adults: A Prospective Cohort Study.

ABSTRACT: Background NT-proBNP (N-terminal pro-B-type natriuretic peptide) is strongly associated with mortality in patients with heart failure. Prior studies, primarily in middle-aged and older populations, have suggested that NT-proBNP has prognostic value in ambulatory adults. Methods and Results We conducted a prospective cohort analysis of adults, aged ≥20 years, in the nationally representative 1999 to 2004 National Health and Nutrition Examination Survey, to characterize the association of NT-proBNP with mortality in the general US adult population overall and by age, race and ethnicity, and body mass index. We used Cox regression to characterize associations of NT-proBNP with all-cause and cardiovascular disease (CVD) mortality through 2019, adjusting for demographics and cardiovascular risk

SUBMITTER: Echouffo-Tcheugui JB 

PROVIDER: S-EPMC10382006 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature