Prediction model for long-term seizure and developmental outcomes among children with infantile epileptic spasms syndrome.

ABSTRACT:

Introduction

Children with infantile epileptic spasms syndrome (IESS) are likely to experience poor outcomes. Researchers have investigated the factors related to its long-term prognosis; however, none of them developed a predictive model.

Objective

This study aimed to clarify the factors that influence the long-term prognosis of seizures and their development and to create a prediction model for IESS.

Materials and methods

We conducted a retrospective cohort study enrolling participants diagnosed with IESS at the Tottori University Hospital. We examined the seizure and developmental status at 3 and 7 years after the IESS onset and divided the participants into favorable and poor outcome groups. Subsequently, we analyzed the factors associated with the poor outcome gr

SUBMITTER: Arai Y 

PROVIDER: S-EPMC10382128 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature