Clinical Outcome Measure Crosswalks in Alzheimer's Disease: A Systematic Review.

ABSTRACT:

Background

A key challenge in studies that model outcomes, disease progression, and cost-effectiveness of existing and emerging dementia treatments is the lack of conversion criteria to translate, or 'crosswalk', scores on multiple measurement scales. Clinical status in dementia is commonly characterized in the cognitive, functional, and behavioral domains.

Objective

We conducted a systematic review of peer-reviewed dementia measure crosswalks in the three domains.

Methods

We systematically reviewed published literature for crosswalks between scales used to measure cognitive, functional, or behavioral outcomes in Alzheimer's and related dementias. The search was conducted in PubMed, and additional crosswalks were identified through snowballing and expert input from de

SUBMITTER: Hlavka JP 

PROVIDER: S-EPMC10382157 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature