Bone mineral density and its relationship with ground reaction force characteristics during gait in young adults with Prader-Willi Syndrome.

ABSTRACT:

Introduction

The incidence of osteopenia and osteoporosis is of concern in adults with Prader-Willi syndrome (PWS). Walking generates reaction forces that could stimulate bone mineralization and is popular in people with PWS. This study compared bone parameters and ground reaction forces (GRF) during gait between young adults with PWS and without PWS and explored associations between bone and GRFs during gait.

Methods

10 adults with PWS, 10 controls with obesity (OB) and 10 with normal weight (NW) matched on sex participated. Segmental and full body dual-energy x-ray absorptiometry scans provided femoral neck, spine, total body minus the head bone mineral density (BMD), bone mineral content (BMC). Vertical GRF, vertical impulse, posterior force and negative impulse were meas

SUBMITTER: Rubin DA 

PROVIDER: S-EPMC10382280 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature