The Ontology of Biological Attributes (OBA)-computational traits for the life sciences.

ABSTRACT: Existing phenotype ontologies were originally developed to represent phenotypes that manifest as a character state in relation to a wild-type or other reference. However, these do not include the phenotypic trait or attribute categories required for the annotation of genome-wide association studies (GWAS), Quantitative Trait Loci (QTL) mappings or any population-focussed measurable trait data. The integration of trait and biological attribute information with an ever increasing body of chemical, environmental and biological data greatly facilitates computational analyses and it is also highly relevant to biomedical and clinical applications. The Ontology of Biological Attributes (OBA) is a formalised, species-independent collection of interoperable phenotypic trait categories that is inten

SUBMITTER: Stefancsik R 

PROVIDER: S-EPMC10382347 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature