A multi-analyte screening method for the rapid detection of illicit adulterants in dietary supplements using a portable SERS analyzer.

ABSTRACT: The popularity and number of dietary supplements on the health market have experienced an unprecedented boost in recent years. Simultaneously, their increased use has been accompanied by an increase in acute intoxication cases linked to the adulteration of these products with illicit and undeclared substances. In this study, a SERS-based screening methodology was developed to rapidly detect illegally added pharmaceutically active substances to dietary supplements. A portable analyzer and silver printed-SERS substrates were used to enhance the signal, requiring less than 20 min of sample preparation prior to the analysis. The method was successful in the qualitative identification of eleven out of twenty-three illicit adulterants in the dietary supplements; it could detect the target compou

SUBMITTER: Rizzo S 

PROVIDER: S-EPMC10382631 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature