Identifying Imaging Predictors of Intermediate Age-Related Macular Degeneration Progression.

ABSTRACT:

Purpose

Intermediate age-related macular degeneration (iAMD) is a risk factor for progression to advanced stages, but rates of progression vary between individuals. Predicting individual risk is advantageous for programing timely and effective treatment and for patient stratification into future clinical trials.

Methods

We conducted a prospective and noninterventional study following patients with iAMD for 24 months. Optical coherence tomography parameters related with drusen, hyper-reflective foci (HRF), presence of incomplete retinal pigment epithelial and outer retinal atrophy (iRORA) and ellipsoid zone (EZ) status were explored at the baseline. Patients were reclassified at the end of the follow-up period and divided according to their progression. A risk prediction mode

SUBMITTER: Flores R 

PROVIDER: S-EPMC10382994 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature