Neuroendocrine Effects on the Risk of Metabolic Syndrome in Children.

ABSTRACT: The endocrine and nervous systems reciprocally interact to manage physiological individual functions and homeostasis. The nervous system modulates hormone release through the hypothalamus, the main cerebrally specialized structure of the neuroendocrine system. The hypothalamus is involved in various metabolic processes, administering hormone and neuropeptide release at different levels. This complex activity is affected by the neurons of various cerebral areas, environmental factors, peripheral organs, and mediators through feedback mechanisms. Therefore, neuroendocrine pathways play a key role in metabolic homeostasis control, and their abnormalities are associated with the development of metabolic syndrome (MetS) in children. The impaired functioning of the genes, hormones, and neuropept

SUBMITTER: Scorrano G 

PROVIDER: S-EPMC10383317 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature