Innovative Delivery and Release Systems for Antioxidants and Other Active Substances in the Treatment of Cancer.

ABSTRACT: Cancer is one of the major diseases leading to death worldwide, and the fight against the disease is still challenging. Cancer diseases are usually associated with increased oxidative stress and the accumulation of reactive oxygen and nitrogen species as a result of metabolic alterations or signaling aberrations. While numerous antioxidants exhibit potential therapeutic properties, their clinical efficiency against cancer is limited and even unproven. Conventional anticancer antioxidants and drugs have, among others, the great disadvantage of low bioavailability, poor targeting efficiency, and serious side effects, constraining their use in the fight against diseases. Here, we review the rationale for and recent advances in potential delivery systems that could eventually be employed in cl

SUBMITTER: Sezgin-Bayindir Z 

PROVIDER: S-EPMC10383431 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature