Serum Concentrations of Benzaldehyde, Isopentanaldehyde and Sex Hormones: Evidence from the National Health and Nutrition Examination Survey.

ABSTRACT: Exposure to environmental chemicals could disturb the balance of sex hormones. However, the studies on Benzaldehyde, Isopentanaldehyde exposure and sex hormones are still limited. Based on the data of 1064 participants in the National Health and Nutrition Examination Survey (NHANES), we used the linear regression model and restricted cubic spline (RCS) model to evaluate the associations of Benzaldehyde/Isopentanaldehyde exposure with testosterone (TT), estradiol (E2), sex hormone binding globulin (SHBG), free androgen index (FAI) and the ratio of TT to E2 (TT/E2). A ln-unit increase in Benzaldehyde was associated with lower TT (β = -0.048, P = 0.030) and E2 (β = -0.094, P = 0.046) in all participants. After further adjustment for menopausal status, Benzaldehyde was negatively

SUBMITTER: Mao Z 

PROVIDER: S-EPMC10383974 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature