The Association between Gestational Diabetes and the Microbiome: A Systematic Review and Meta-Analysis.

ABSTRACT: Gestational diabetes, affecting about 10% of pregnancies, is characterized by impaired glucose regulation and can lead to complications for health of pregnant women and their offspring. The microbiota, the resident microbes within the body, have been linked to the development of several metabolic conditions. This systematic review with meta-analysis aims to summarize the evidence on the differences in microbiota composition in pregnant women with gestational diabetes and their offspring compared to healthy pregnancies. A thorough search was conducted in the PubMed, Scopus, and Web of Science databases, and data from 21 studies were analyzed utilizing 41 meta-analyses. In the gut microbiota, Bifidobacterium and Alistipes were found to be more abundant in healthy pregnancies, while Roseburia

SUBMITTER: Teixeira RA 

PROVIDER: S-EPMC10385443 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature