Evaluation of the Performance of the Novodiag^® Stool Parasites Assay for the Detection of Intestinal Protozoa and Microsporidia.

ABSTRACT:

Objectives

We aimed to assess the performance of the Novodiag^® Stool Parasites (NSP) assay in the diagnosis of the most common intestinal protozoan and microsporidia infections.

Methods

A panel of 167 selected stool samples was retrospectively analysed with the NSP assay and compared to routine microscopy and qPCR methods for the detection of pathogenic protozoa and microsporidia.

Results

Whereas specificity was high for all protozoa and microsporidia, NSP sensitivity was strongly dependent on the comparative method used as reference. When compared to microscopic methods, NSP sensitivity was high (96.7 to 100%) for Blastocystis hominis, Entamoeba histolytica and Cyclospora cayetanensis but was lower for Giardia intestinalis (85.2

SUBMITTER: Chauvin P 

PROVIDER: S-EPMC10385646 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature