Development of a chemically defined medium for Paenibacillus polymyxa by parallel online monitoring of the respiration activity in microtiter plates.

ABSTRACT:

Background

One critical parameter in microbial cultivations is the composition of the cultivation medium. Nowadays, the application of chemically defined media increases, due to a more defined and reproducible fermentation performance than in complex media. In order, to improve cost-effectiveness of fermentation processes using chemically defined media, the media should not contain nutrients in large excess. Additionally, to obtain high product yields, the nutrient concentrations should not be limiting. Therefore, efficient medium optimization techniques are required which adapt medium compositions to the specific nutrient requirements of microorganisms.

Results

Since most Paenibacillus cultivation protocols so far described in literature are based on complex ingredients, in

SUBMITTER: Goldmanns J 

PROVIDER: S-EPMC10385886 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature