Genomic Analysis of Clostridioides difficile Recovered from Horses in Western Australia.

ABSTRACT: Clostridioides difficile poses an ongoing threat as a cause of gastrointestinal disease in humans and animals. Traditionally considered a human healthcare-related disease, increases in community-associated C. difficile infection (CDI) and growing evidence of inter-species transmission suggest a wider perspective is required for CDI control. In horses, C. difficile is a major cause of diarrhoea and life-threatening colitis. This study aimed to better understand the epidemiology of CDI in Australian horses and provide insights into the relationships between horse, human and environmental strains. A total of 752 faecal samples from 387 Western Australian horses were collected. C. difficile was isolated from 104 (30.9%) horses without gastrointestinal signs and 19 (

SUBMITTER: Hain-Saunders NMR 

PROVIDER: S-EPMC10386058 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature