ROGUE: an R Shiny app for RNA sequencing analysis and biomarker discovery.

ABSTRACT:

Background

The growing power and ever decreasing cost of RNA sequencing (RNA-Seq) technologies have resulted in an explosion of RNA-Seq data production. Comparing gene expression values within RNA-Seq datasets is relatively easy for many interdisciplinary biomedical researchers; however, user-friendly software applications increase the ability of biologists to efficiently explore available datasets.

Results

Here, we describe ROGUE (RNA-Seq Ontology Graphic User Environment, https://marisshiny.

Research

chop.edu/ROGUE/ ), a user-friendly R Shiny application that allows a biologist to perform differentially expressed gene analysis, gene ontology and pathway enrichment analysis, potential biomarker identification, and advanced statistical analyses. We use ROGUE to identi

SUBMITTER: Farrel A 

PROVIDER: S-EPMC10386769 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature