Prenatal tobacco exposure associations with physical health and neurodevelopment in the ABCD cohort.

ABSTRACT:

Objective

To investigate the strength and reproducibility of the teratogenic impact of prenatal tobacco exposure (PTE) on child physical health and neurodevelopmental outcomes, in the context of intersecting sociodemographic and other prenatal correlates, and test if early postnatal health mediates PTE associations with childhood outcomes.

Method

Among 9-10-year-olds (N = 8,803) in the Adolescent Brain Cognitive Development Study, linear mixed-effect models tested PTE associations with birth and childhood outcomes of physical health, cognitive performance, and brain structure, controlling for confounding sociodemographic and prenatal health correlates. Mediation analysis tested the extent to which health at birth explained the associations between PTE and childhood ou

SUBMITTER: Gonzalez MR 

PROVIDER: S-EPMC10387130 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature