Unusual presentation of antisynthetase syndrome: a case series and review of the literature.

ABSTRACT:

Background

Antisynthetase syndrome is an inflammatory myopathy that is characterized by the presence of anti-aminoacyl-tRNA synthetase antibodies. Only 30% of those who suffer from the disease can be identified. We present three Hispanic cases of antisynthetase syndrome with unusual clinical pictures were extended myositis panel results enable disease diagnosis and treatment.

Case presentation

A 57-year-old Hispanic/Latino female with an erythematous scaly plaque, unresolved fever and non-immune haemolytic anaemia in whom inpatient work-up for fever of unknown origin was positive for anti-PL12 positive myositis extended panel. A 72-year-old Hispanic/Latino male with amyopathic weakness syndrome and mechanic hands in whom impatient work-up was relevant for proximal muscle upt

SUBMITTER: Estrada-Maya J 

PROVIDER: S-EPMC10387198 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature