Subjective and objective sleep alterations in medication-naive children and adolescents with autism spectrum disorder: a systematic review and meta-analysis.

ABSTRACT:

Aims

This study aimed to summarize the evidence on sleep alterations in medication-naïve children and adolescents with autism spectrum disorder (ASD).

Methods

We systematically searched PubMed/Medline, Embase and Web of Science databases from inception through March 22, 2021. This study was registered with PROSPERO (CRD42021243881). Any observational study was included that enrolled medication-naïve children and adolescents with ASD and compared objective (actigraphy and polysomnography) or subjective sleep parameters with typically developing (TD) counterparts. We extracted relevant data such as the study design and outcome measures. The methodological quality was assessed through the Newcastle-Ottawa Scale (NOS). A meta-analysis was carried out using the random-effects mod

SUBMITTER: Kim H 

PROVIDER: S-EPMC10387490 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature