Protocol: carrageenan for the prevention of oral HPV infection - a feasibility randomised clinical trial.

ABSTRACT:

Introduction

Head and neck cancers (HNCs) are a significant health burden worldwide. Oral human papillomavirus (HPV) infection is a major risk factor for HNCs. Unfortunately, currently available prophylactic vaccines have limited coverage and potential for HPV type replacement. Carrageenan, a natural product extracted from marine red algae, has demonstrated potency as an HPV inhibitor and could offer a potential alternative to prevent HPV-related diseases, including oral HPV infection. However, there is a lack of clinical studies on the effect of carrageenan on oral HPV infections. As a first step to address this gap, we propose a randomised controlled trial (RCT) to evaluate the feasibility of conducting a larger multicentric RCT to investigate the effect of a carrageenan mouthwas

SUBMITTER: Alli BY 

PROVIDER: S-EPMC10387654 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature