Ontology highlight
ABSTRACT:
SUBMITTER: Kayser S
PROVIDER: S-EPMC10388269 | biostudies-literature | 2023 Aug
REPOSITORIES: biostudies-literature
Kayser Sabine S Martínez-Cuadrón David D Rodriguez-Veiga Rebeca R Hänel Mathias M Tormo Mar M Schäfer-Eckart Kerstin K Botella Carmen C Stölzel Friedrich F Del Castillo Teresa Bernal TB Keller Ulrich U Rodriguez-Medina Carlos C Held Gerhard G Amigo Maria-Luz ML Schliemann Christoph C Colorado Mercedes M Kaufmann Martin M Garcia Manuel Barrios MB Krause Stefan W SW Görner Martin M Jost Edgar E Steffen Björn B Zukunft Sven S Platzbecker Uwe U Ho Anthony D AD Baldus Claudia D CD Serve Hubert H Müller-Tidow Carsten C Thiede Christian C Bornhäuser Martin M Montesinos Pau P Röllig Christoph C Schlenk Richard F RF
Haematologica 20230801 8
We retrospectively studied 97 acute myeloid leukemia patients with trisomy 19 (median age at diagnosis 57 years; range, 17- 83 years) treated between 2001 and 2019 within two multicenter study groups. Trisomy 19 occurred alone in ten (10.5%) patients, with additional abnormalities being present in non-complex karyotypes in eight (8%) patients and in complex karyotypes in 79 (82%) patients. Altogether, karyotypes characterized by trisomies only were present in 27 (28%) patients. Data on response ...[more]