The deep learning algorithm estimates chest radiograph-based sex and age as independent risk factors for future cardiovascular outcomes.

ABSTRACT:

Objectives

Chest X-rays (CXRs) convey much illegible physiological information that deep learning model (DLM) has been reported interpreting successfully. Since the electrocardiogram age established by DLM was revealed as a heart biological marker, we hypothesize that CXR age has similar potential to describe the heart and lung states. Therefore, we developed a DLM to predict sex and age through CXR and analyzed its relation with future cardiovascular diseases (CVD).

Methods

A total of 90,396 CXRs aged 20 to 90 were collected and separated into a development set with 53,102 CXRs and demographic information pairs, a tuning set with 7073 pairs, an internal validation set with 17,364 pairs, and an external validation set with 12,857 pairs. The study trained DLM with development

SUBMITTER: Liao HC 

PROVIDER: S-EPMC10388631 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature