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Exploring genetic loci of type 2 diabetes and cancer: a review.


ABSTRACT: Diabetes and cancer are two heterogenous diseases which are rapidly increasing in prevalence globally. A link between these two non-communicable diseases was first identified over 100 years ago; however, recent epidemiological studies and advances in genomic research have provided greater insight into the association between diabetes and cancer. Epidemiological studies have suggested that individuals with diabetes have an increased risk of several types of cancer (including liver, pancreas, colorectal, breast, and endometrial) and an increased risk of cancer mortality. However, this increased risk is not observed in all cancers, for example, there is a reduced risk of prostate cancer in individuals with diabetes. It has also been observed that cancer patients have an increased risk of deve

SUBMITTER: Endicott M 

PROVIDER: S-EPMC10388678 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature