Impact of vitamin B12 on the reproductive health of women with sickle cell disease: a narrative review.

ABSTRACT: Sickle cell disease (SCD) poses an increased risk of infertility, pregnancy complications and maternal and perinatal mortality among women of reproductive age. This risk is particularly higher for women in sub-Saharan Africa, where the disease burden is highest and access to comprehensive health care is limited, as well as in other countries with a high SCD prevalence due to migration. Disease modifying treatments for SCD could directly and indirectly harm the ovaries, potentially compromising quality and quantity of existing oocytes. Therefore, it is essential to explore alternative interventions, such as nutritional modifications that are less harmful and cost-effective in order to improve reproductive outcomes, and enhance the overall well-being of both mother and child in this populati

SUBMITTER: Agbalalah T 

PROVIDER: S-EPMC10388680 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature