Sporadic Primary Pheochromocytoma: A Prospective Intraindividual Comparison of Six Imaging Tests (CT, MRI, and PET/CT Using ⁶⁸Ga-DOTATATE, FDG, ¹⁸F-FDOPA, and ¹⁸F-FDA).

ABSTRACT: BACKGROUND. Recent professional society guidelines for radionuclide imaging of sporadic pheochromocytoma (PHEO) recommend ¹⁸F-fluorodihydroxyphenylala-nine (¹⁸F-FDOPA) as the radiotracer of choice, deeming ⁶⁸Ga-DOTATATE and FDG to be second- and third-line agents, respectively. An additional agent, ¹⁸F-fluorodopamine (¹⁸F-FDA), remains experimental for PHEO detection. A paucity of research has performed head-to-head comparison among these agents. OBJECTIVE. The purpose of this study was to perform an intraindividual comparison of ⁶⁸Ga-DOTATATE PET/CT, FDG PET/CT, ¹⁸F-FDOPA PET/CT, ¹⁸F-FDA PET/CT, CT, and MRI in visualization of sporadic primary PHEO. METHODS. This prospective study

SUBMITTER: Jha A 

PROVIDER: S-EPMC10389669 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature