Detection of vaccine-derived polioviruses in Mexico using environmental surveillance.

ABSTRACT:

Background

Early detection and control of vaccine-derived poliovirus (VDPV) emergences are essential to secure the gains of polio eradication.

Methods

Serial sewage samples were collected in 4 towns of Mexico before, throughout, and after the May 2010 oral poliovirus vaccine (OPV) mass immunization campaign. Isolation and molecular analysis of polioviruses from sewage specimens monitored the duration of vaccine-related strains in the environment and emergence of vaccine-derived polioviruses in a population partially immunized with inactivated poliovirus vaccine (IPV).

Results

Sabin strains were identified up to 5-8 weeks after the campaign in all towns; in Aguascalientes, 1 Sabin 3 was isolated 16 weeks after the campaign, following 7 weeks with no Sabin strains detec

SUBMITTER: Esteves-Jaramillo A 

PROVIDER: S-EPMC10389690 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature