Patient Experiences with Clostridioides difficile Infection and Its Treatment: A Systematic Literature Review.

ABSTRACT:

Introduction

Clostridioides difficile infection (CDI) is a globally recognized cause of morbidity and mortality with devastating effects on health-related quality of life (HRQoL). The objective of this study was to conduct the first systematic literature review (SLR) to assess the humanistic burden of CDI on patient experiences, including HRQoL and related constructs, and attitudes towards treatment alternatives.

Methods

An SLR was conducted to identify peer-reviewed articles that assessed CDI, including recurrent CDI (rCDI), and patient-reported outcomes or HRQoL. PubMed, Embase, and the Cochrane Collaboration abstracting services were used to conduct literature searches from 2010 to 2021 in the English language. This SLR was conducted in accordance with Preferred Reporting

SUBMITTER: Armstrong EP 

PROVIDER: S-EPMC10390453 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature