Sugar restriction and blood ingestion shape divergent immune defense trajectories in the mosquito Aedes aegypti.

ABSTRACT: Immune defense is comprised of (1) resistance: the ability to reduce pathogen load, and (2) tolerance: the ability to limit the disease severity induced by a given pathogen load. The study of tolerance in the field of animal immunity is fairly nascent in comparison to resistance. Consequently, studies which examine immune defense comprehensively (i.e. considering both resistance and tolerance in conjunction) are uncommon, despite their exigency in achieving a thorough understanding of immune defense. Furthermore, understanding tolerance in arthropod disease vectors is uniquely relevant, as tolerance is essential to the cyclical transmission of pathogens by arthropods. Here, we tested the effect(s) of dietary sucrose concentration and blood ingestion on resistance and tolerance to Escherich

SUBMITTER: Magistrado D 

PROVIDER: S-EPMC10390476 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature