Investigating structural and functional aspects of the brain's criticality in stroke.

ABSTRACT: This paper addresses the question of the brain's critical dynamics after an injury such as a stroke. It is hypothesized that the healthy brain operates near a phase transition (critical point), which provides optimal conditions for information transmission and responses to inputs. If structural damage could cause the critical point to disappear and thus make self-organized criticality unachievable, it would offer the theoretical explanation for the post-stroke impairment of brain function. In our contribution, however, we demonstrate using network models of the brain, that the dynamics remain critical even after a stroke. In cases where the average size of the second-largest cluster of active nodes, which is one of the commonly used indicators of criticality, shows an anomalous behavior, i

SUBMITTER: Janarek J 

PROVIDER: S-EPMC10390586 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature