A bioinformatic analysis of zinc transporters in intestinal Lactobacillaceae.

ABSTRACT: As the second most abundant transition element and a crucial cofactor for many proteins, zinc is essential for the survival of all living organisms. To maintain required zinc levels and prevent toxic overload, cells and organisms have a collection of metal transport proteins for uptake and efflux of zinc. In bacteria, metal transport proteins are well defined for model organisms and many pathogens, but fewer studies have explored metal transport proteins, including those for zinc, in commensal bacteria from the gut microbiota. The healthy human gut microbiota comprises hundreds of species and among these, bacteria from the Lactobacillaceae family are well documented to have various beneficial effects on health. Furthermore, changes in dietary metal intake, such as for zinc and iron, are fr

SUBMITTER: Huynh U 

PROVIDER: S-EPMC10391621 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature