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Evaluation of the MVCT-based radiomic features as prognostic factor in patients with head and neck squamous cell carcinoma.


ABSTRACT:

Background

Megavoltage computed tomography (MVCT) images acquired during each radiotherapy session may be useful for delta radiomics. However, no studies have examined whether the MVCT-based radiomics has prognostic power. Therefore, the purpose of this study was to examine the prognostic power of the MVCT-based radiomics for head and neck squamous cell carcinoma (HNSCC) patients.

Methods

100 HNSCC patients who received definitive radiotherapy were analyzed and divided into two groups: training (n = 70) and test (n = 30) sets. MVCT images obtained using TomoTherapy for the first fraction of radiotherapy and planning kilovoltage CT (kVCT) images obtained using Aquilion LB CT scanner were analyzed. Primary gross tumor volume (GTV) was propagated from kVCT to MVCT images using

SUBMITTER: Abe K 

PROVIDER: S-EPMC10391970 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature