A rare case of severe leptospirosis infection presenting as septic shock in a non-endemic area: a case report and literature review.

ABSTRACT:

Background

Leptospirosis is a zoonosis caused by spirochete "genus" leptospira. The clinical presentations of leptospirosis range from an influenza-like presentation of fever and myalgia, to severe forms. Leptospirosis can potentially lead to a misdiagnosis or delay in diagnosis when clinical similarities exist.

Case presentation

A 63-year-old man presented with fever, shock and thrombocytopenia followed by diffuse pulmonary hemorrhage. Peripheral blood Metagenomic Next-generation Sequencing (mNGS) reported Leptospira interrogans. The patient was treated with piperacillin-tazobactam (TZP) plus doxycycline and improved dramatically after 7 days.

Conclusion

We conclude that leptospirosis can potentially lead to a misdiagnosis or delay in diagnosis. Correctly evaluation

SUBMITTER: Dai J 

PROVIDER: S-EPMC10391985 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature