Ontology highlight
ABSTRACT:
SUBMITTER: Zhao R
PROVIDER: S-EPMC10392945 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Zhao Rou R Cao Guanjie G Zhang Baogui B Wei Li L Zhang Xiaobei X Jin Meng M He Baoyu B Zhang Bin B He Zhun Z Bie Qingli Q
Frontiers in oncology 20230718
Regulatory T cells (Tregs) are an important component of the tumor microenvironment; however, the interaction between Tregs and gastric cancer cells is not completely understood. Recent studies have shown that Tregs participate in cancer cell stemness maintenance. In this study, we performed single-cell RNA sequencing of gastric cancer and adjacent tissues and found that Tregs with high TNF expression were recruited to gastric cancer tissues and were significantly correlated with patient surviva ...[more]