A multidisciplinary lifestyle program for rheumatoid arthritis: the 'Plants for Joints' randomized controlled trial.

ABSTRACT:

Objective

To determine the effect of a multidisciplinary lifestyle program in patients with RA with low-moderate disease activity.

Methods

In the 'Plants for Joints' (PFJ) parallel-arm, assessor-blind randomized controlled trial, patients with RA and 28-joint DAS (DAS28) ≥2.6 and ≤5.1 were randomized to the PFJ or control group. The PFJ group followed a 16-week lifestyle program based on a whole-food plant-based diet, physical activity and stress management. The control group received usual care. Medication was kept stable 3 months before and during the trial whenever possible. We hypothesized that PFJ would lower disease activity (DAS28). Secondary outcomes included anthropometric, metabolic and patient-reported measures. An intention-to-treat analysis with a linear mixed m

SUBMITTER: Walrabenstein W 

PROVIDER: S-EPMC10393439 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature