Evaluating the relationship between community water and sanitation access and the global burden of antibiotic resistance: an ecological study.

ABSTRACT:

Background

Antibiotic resistance is a leading cause of death, with the highest burden occurring in low-resource settings. There is little evidence on the potential for water, sanitation, and hygiene (WASH) access to reduce antibiotic resistance in humans. We aimed to determine the relationship between the burden of antibiotic resistance in humans and community access to drinking water and sanitation.

Methods

In this ecological study, we linked publicly available, geospatially tagged human faecal metagenomes (from the US National Center for Biotechnology Information Sequence Read Archive) with georeferenced household survey datasets that reported access to drinking water sources and sanitation facility types. We used generalised linear models with robust SEs to estimate the r

SUBMITTER: Fuhrmeister ER 

PROVIDER: S-EPMC10393780 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature