Oesophageal varices predict complications in compensated advanced non-alcoholic fatty liver disease.

ABSTRACT:

Background & aims

We aimed to evaluate the impact of oesophageal varices (OV) and their evolution on the risk of complications of compensated advanced chronic liver disease (cACLD) caused by non-alcoholic fatty liver disease (NAFLD). We also assessed the accuracy of non-invasive scores for predicting the development of complications and for identifying patients at low risk of high-risk OV.

Methods

We performed a retrospective assessment of 629 patients with NAFLD-related cACLD who had baseline and follow-up oesophagogastroduodenoscopy and clinical follow-up to record decompensation, portal vein thrombosis (PVT), and hepatocellular carcinoma.

Results

Small and large OV were observed at baseline in 30 and 15.9% of patients, respectively. The 4-year incidence of OV from

SUBMITTER: Pennisi G 

PROVIDER: S-EPMC10393808 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature