Trends in laboratory-confirmed bacterial meningitis (2012-2019): national observational study, England.

ABSTRACT:

Background

Bacterial meningitis is associated with significant morbidity and mortality worldwide. We aimed to describe the epidemiology, aetiology, trends over time and outcomes of laboratory-confirmed bacterial meningitis in England during 2012-2019.

Methods

UK Health Security Agency routinely receives electronic notifications of confirmed infections from National Health Service hospital laboratories in England. Data were extracted for positive bacterial cultures, PCR-positive results for Neisseria meningitidis or Streptococcus pneumoniae from cerebrospinal fluid and positive blood cultures in patients with clinical meningitis.

Findings

During 2012-19, there were 6554 laboratory-confirmed cases. Mean annual incidence was 1.49/100,000, which remained sta

SUBMITTER: Subbarao S 

PROVIDER: S-EPMC10393823 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature