Risks of alcohol and drug use disorders in prostate cancer survivors: a national cohort study.

ABSTRACT:

Background

Prostate cancer (PC) survivors may potentially use substances to cope with psychological distress or poorly controlled physical symptoms. Little is known, however, about the long-term risks of alcohol use disorder (AUD) or drug use disorders in men with PC.

Methods

A national cohort study was conducted in Sweden of 180 189 men diagnosed with PC between 1998 and 2017 and 1 801 890 age-matched population-based control men. AUD and drug use disorders were ascertained from nationwide records through 2018. Cox regression was used to compute hazard ratios (HRs) while adjusting for sociodemographic factors and prior psychiatric disorders. Subanalyses examined differences by PC treatment from 2005 to 2017.

Results

Men with high-risk PC had increased risks of both A

SUBMITTER: Crump C 

PROVIDER: S-EPMC10393870 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature