Uropathogenic Escherichia coli population structure and antimicrobial susceptibility in Norfolk, UK.

ABSTRACT:

Background

Urinary tract infections (UTIs) are a frequent cause for visits to primary care providers. In alignment globally, uropathogenic Escherichia coli (UPEC) are the main aetiological agent for UTIs in Norfolk and are increasingly difficult to treat due to multi-drug resistance.

Objectives

We set out to identify which clonal groups and resistance genes are disseminating in the community and hospitals in Norfolk, the first study of its kind for UPEC in this region.

Methods

We collected 199 clinical E. coli isolates causing UTIs in the community and hospital from the Clinical Microbiology laboratory at Norfolk and Norwich University Hospital between August 2021 and January 2022. These were whole-genome sequenced using the Illumina and MinION platforms for in silico

SUBMITTER: Carter C 

PROVIDER: S-EPMC10393884 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature