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Dysfunctional connectivity as a neurophysiologic mechanism of disorders of consciousness: a systematic review.


ABSTRACT:

Introduction

Disorders of consciousness (DOC) has been an object of numbers of research regarding the diagnosis, treatment and prognosis in last few decades. We believe that the DOC could be considered as a disconnection syndrome, although the exact mechanisms are not entirely understood. Moreover, different conceptual frameworks highly influence results interpretation. The aim of this systematic review is to assess the current knowledge regarding neurophysiological mechanisms of DOC and to establish possible influence on future clinical implications and usage.

Methods

We have conducted a systematic review according to PRISMA guidelines through PubMed and Cochrane databases, with studies being selected for inclusion via a set inclusion and exclusion criteria.

Results

SUBMITTER: Plosnic G 

PROVIDER: S-EPMC10394244 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature